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Writer's pictureHeather Hauptman

Another way to stop cancer, hopeful new research from MD Anderson.


The latest research on ovarian cancer reveals 2 non-toxic treatments out of MD Anderson that take a different look at ovarian cancer.


Oftentimes ovarian cancer is diagnosed in later stages, resulting in a more dangerous cancer compared to others with more obvious signs and symptoms. Continued ovarian cancer research in 2022, therefore is crucial in increasing longevity and quality of life for those who are fighting it.


Two researchers out of MD Anderson are looking to do both those things.


Dr. Vahid Afsher-Kharghan M.D., is interested in fighting ovarian cancer by interfering in the proteins that help ovarian cancer cells grow. The complement system, once thought part of the body’s defense against cancer cell growth (a subsystem of the immune system), might instead contribute to cancer cell growth. The complement system produces proteins that in effect feed the ovarian cancer cells. Dr. Afsher-Kharghan and his associates at MD Anderson are working to block this gene expression, thereby preventing the protein production and cancer growth. The hope is that this treatment would work along with ongoing ovarian cancer treatment, but with few side effects.


Dr.Yurfei Wen Ph.D in her research is working on blocking a contributor to ovarian cancer cell growth from a different angle. Prolactin is a hormone that has been found to contribute to ovarian cancer cell growth. Dr. Wen and her colleagues at MD Anderson are working with a drug they are calling G129R. What G129R does, in effect, is block cancer cell growth by blocking prolactin. What remains is a starved cancer cell that is therefore damaged or destroyed. Dr. Wen is currently in the lab studying G129R in cancer resistant to chemotherapy, and is hoping to take G129R to clinical trials. Dr. Wen hopes that G129R will work in conjunction with other more traditional ovarian cancer treatments.


The hope is that with new and continued research, we can help our loved ones fight ovarian cancer and maintain quality of life while doing so.


https://www.mdanderson.org/cancerwise/researchers-explore-new-possibilities-for-ovarian-cancer-treatment.h00-159538956.html



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